Blood is the life giving river that flows within us all. Endlessly, day in, day out, blood is flowing around the veins and arteries of all living vertebrates. In the same way that rivers nurture and cleanse the land, so our blood feeds, fuels and cleanses our bodies.
Blood is basically a fluid called plasma, a relatively clear liquid which contains dissolved nutrients and waste products in ever changing amounts. Mammal blood is red though not clear, this is because besides the dissolved constituents it also contains a variety of cells, i.e. red cells, white cells and platelets. In all mammals the average ratios of the different components of blood vary between different groups. In mankind blood is about 45% cells and 55% plasma.
Red blood cells are the main everyday workers of blood. They are called erythrocytes and they are responsible for carrying oxygen from the lungs to the cells of the body and carbon dioxide back to the lungs where it can be exhaled. Red blood cells are able to do this because they contain a pigment called haemoglobin. There are about 4,500,000 red blood cells in every cubic millimetre of a man's blood. For some reason females normally have slightly less. In humans, blood occurs in four main different groups resulting from the presence or absence of 2 different antigens (a type of protein) on the surface of red blood cells and the corresponding antibodies (also proteins) dissolved in the plasma. The two antigens are called A and B. So if you have A antigen on your red blood cells, then you are blood group A; if antigen B, then you are blood group B; if both antigens, then you are AB; if neither antigen, then you have blood group O. Another important antigen on red blood cells is the rhesus antigen. If you have this then you are rhesus positive, if not then you are rhesus negative. Thus most people have their blood groups described as O- (that's me) or A+, etc. Finally, erythrocytes are very unusual cells in that they do not have a nucleus.
White blood cells are part of the body's defence against foreign invaders, bacteria etc., which can harm the system. They can be divided into two sorts depending on where they are made. Lymphocytes which are produced in lymphatic tissues and leucocytes which are produced in bone marrow. There are at least 3 different types of lymphocytes and two types of leucocytes. They work in different ways and against different invaders; some are like amoebae and engulf unwanted bodies whole, others act like a pack of wolves surrounding, sticking to and smothering any foreign body.
Platelets are minute colourless cells. They are also produced in the bone marrow. Platelets play a role in blood clotting in wounds, and action designed to prevent excessive blood loss from small wounds.
Though Red blood cells (erythrocytes) are the main vehicle for carrying oxygen away from the lungs, they are not the main method of carrying carbon dioxide back to the lungs. In fact, 85% of the carbon dioxide is carried as dissolved sodium bicarbonate in the plasma.
Blood travels around the body in special vessels or tubes called arteries and veins which branchiate (divide like the branches of a tree) and become smaller as they get further away from the heart. Arteries have thicker, stronger walls than veins which helps them to withstand the pressures generated by the pumping heart. Arteries therefore carry the blood away from the heart and to the various parts of the body while veins carry blood from the body back to the heart.
Normally, this means that the blood in the arteries is well oxygenated and therefore red, while blood in veins is deoxygenated (high in carbon dioxide) and more bluish. This gives rise to the terms arterial and venous blood for oxygenated and deoxygenated blood. There are exceptions to most rules, however, and the exception to this one is that blood going from the lungs to the heart and from the heart to the lungs. Here the blood returning to the heart from the body via the veins is pumped up to the lungs. Because the blood is leaving the heart it is pumped through arteries, but because it has already been around the body it is blue deoxygenated blood. Also, the blood coming back to the heart from the lungs is red oxygenated blood ready to go out to the body organs, but it is travelling in veins.
So blood travels its endless figure of 8 journey around our bodies; Heart - body - heart - lungs - heart body etc. Everyday your system works like this, without rest, holidays or complaints.
The mammal heart has two sides and two chambers (an auricle and a ventricle) in each side. The sides are not connected in adults. Blood flows as oxygenated blood from the left auricle to the left ventricle which pumps it out to the body from where it returns as deoxygenated blood to the right auricle which sends it to the right ventricle which sends it out to the lungs. From here it returns to the left auricle and hence the cycle begin again on and on ...
Heart rate varies, generally in proportion to size thus smaller mammals tend to have higher heart beat rates than larger ones, this applies to other animals as well. The range is quite considerable see below. Diving mammals change their heart rate whilst diving, thus grey seals have a surface heart rate of 120 bpm, (beats per minute), but reduce this to about 10 bpm whilst diving and Harp seals which have a resting heart rate of 83 bpm reduce this to 2.06 on the way down, then it rises to around 10 whilst swimming around and on the way up. The after the first breath of fresh air on returning to the surface its leaps to about 150 bpm for a short while. Hibernating mammals also have greatly reduced Europeantes. Thus a european Hedgehog has a normal heart rate of between 200 and 280 bpm, this decreases to 147 bpm while it is asleep but drops even further to around 5 bpm while it is hibernating. Bats also reduce there heart rates when in torpor during winter in temperate climates thus the heart beat rate of a medium sized bat can go from 700bpm at rest to 1000 when flying to 25 while overwintering.
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